"In 2014 we lost her to ovarian cancer," said event coordinator Bill Wall.
For others it's a celebration of victory.
"Halos can wait. I'm alive now," said Riena Carroll.
But for everyone, it's coming together to defeat cancer.
"All of us are stronger than one of us, and that's evident here tonight because all these people have come out," said Miles Carroll.
The American Cancer Society's flagship event started in Tacoma, Washington in 1985, since then it has evolved into an annual affair in 27 different countries.
At this year's Pocatello event, it featured a survivor's walk, an appearance from the POW MIA Awareness Association, a quilt auction, and plenty of literal and figurative steps towards a cure.
This is Bill Wall's first year as the event coordinator, in 2010 his daughter was diagnosed with ovarian cancer, it was then when they both got involved with Relay.
She passed away in 2014, and she inspired bill to get even more involved.
"I can't let the survivors go. I mean they're almost like your children, I love them all. I've never met a survivor I didn't love," said Wall.
So while everyone may come from different walks of life, their fight against cancer brings them all together.